GLP-1: Acute Effects on Kidney Function in Healthy Men

Completed 12 enrolled Jeppe Skov Novo Nordisk A/S · collab

RandomizedCrossoverDouble-blindBasic science

Summary

The purpose of this study is to investigate how Glucagon-Like Peptide 1 (GLP-1) affects kidney function in healthy young men. The hypothesis is that GLP-1 induces a positive effect on kidney hemodynamics.

Timeline

Start: 2011-05
Primary completion: 2011-12
Completion: 2011-12

Publications

Skov J, Dejgaard A, Frokiaer J, Holst JJ, Jonassen T, Rittig S, Christiansen JS. Glucagon-like peptide-1 (GLP-1): effect on kidney hemodynamics and renin-angiotensin-aldosterone system in healthy men. J Clin Endocrinol Metab. 2013 Apr;98(4):E664-71. doi: 10.1210/jc.2012-3855. Epub 2013 Mar 5.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	GLP-1 (7-36) amide	Unknown	1.5 unknown	Intravenous

Indications

No indication recorded.