drugset / Trial / NCT01333501
Fingolimod Versus Interferon Beta 1b in Cognitive Symptoms
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this pilot study is to evaluate, by means of a specific cognitive test battery (Brief Repeatable Battery and Delis-Kaplan Executive Function System scale), the slowing/reduction of cognitive dysfunction progression in RRMS patients after 18 months of treatment with fingolimod in comparison with interferon beta 1b treatment, and to evaluate which test of the battery is the most sensitive in detecting differences between treatment groups.
Timeline
- Start
- 2011-05
- Primary completion
- 2015-09
- Completion
- 2015-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fingolimod | Small molecule | 0.5 mg | Oral |
| Comparator | Interferon beta-1b | Protein / enzyme biologic | 250 ug | Subcutaneous |