Safety, Tolerability, and Pharmacodynamic Effect Study of PUR118

Summary

The purpose of this study is to establish single and multiple dose safety in healthy subjects and subjects with mild chronic pulmonary obstructive disease (COPD). In addition, the study will evaluate preliminary proof of concept endpoints in COPD subjects such as biomarkers in sputum and mucociliary clearance.

Timeline

Start

2011-02

Primary completion

2012-06

Completion

2012-06

Drugs

Indications