drugset / Trial / NCT01334255

iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV)

NCT01334255

Phase 1 Terminated 12 enrolled Lpath, Inc. Pfizer · collab
RandomizedSingle-groupOpen-labelTreatment

Summary

LT1009-Oph-002 is a Phase 1b study designed to evaluate the safety and potential efficacy of iSONEP following one, two or three injections of iSONEP, as needed, for the treatment of Pigment Epithelial Detachment (PED) secondary to PED Secondary to Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV).

Timeline

Start
2011-03
Primary completion
2012-02
Completion
2012-07

Drugs

EvaluationDrugModalityDoseRoute
Subject sonepcizumab Monoclonal antibody 0.5 mg Intravitreal
Subject sonepcizumab Monoclonal antibody 2 mg Intravitreal

Indications