drugset / Trial / NCT01334255
iSONEP to Treat Persistent Pigment Epithelial Detachment (PED) in Subjects With Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV)
RandomizedSingle-groupOpen-labelTreatment
Summary
LT1009-Oph-002 is a Phase 1b study designed to evaluate the safety and potential efficacy of iSONEP following one, two or three injections of iSONEP, as needed, for the treatment of Pigment Epithelial Detachment (PED) secondary to PED Secondary to Exudative Age-Related Macular Degeneration (AMD) or Polypoidal Choroidal Vasculopathy (PCV).
Timeline
- Start
- 2011-03
- Primary completion
- 2012-02
- Completion
- 2012-07
Outcome
Outcome not reported
Stopped (Business): “Sponsor decision; not safety related”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | sonepcizumab | Monoclonal antibody | 0.5 mg | Intravitreal |
| Subject | sonepcizumab | Monoclonal antibody | 2 mg | Intravitreal |