drugset / Trial / NCT01342549

Treatment Strategy for Alcohol Use Disorders in Veterans With TBI

NCT01342549

Phase 3 Completed 62 enrolled VA Office of Research and Development
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this research study is to understand the effectiveness of valproate (a common mood stabilizer) to further reduce alcohol misuse when given in addition to attending an alcohol rehabilitation program as well as the treatment of mood disorders or PTSD. The main goal of this project is to understand if people receiving valproate will have a better recovery than people receiving the standard treatment for alcohol dependence: naltrexone.

Timeline

Start
2011-09
Primary completion
2015-06
Completion
2015-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Naltrexone Small molecule 50 mg Oral
Comparator Valproate Small molecule 1250 mg
Comparator Valproate Small molecule 2000 mg

Indications