drugset / Trial / NCT01343303
A Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of JNJ-39439335 in Patients With Osteoarthritis
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of this study is to evaluate the safety of multiple oral doses of JNJ-39439335 and to assess how JNJ-39439335 is absorbed (taken in), distributed, metabolized (broken down), and eliminated from the body (referred to as pharmacokinetics) in osteoarthritis patients. This study will also assess the effectiveness of JNJ-39439335 on pain.
Timeline
- Start
- 2011-03
- Primary completion
- —
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MAVATREP | Small molecule | 10 mg | Oral |
| Subject | MAVATREP | Small molecule | 25 mg | Oral |
| Subject | Naproxen | Small molecule | 500 mg | Oral |