drugset / Trial / NCT01344707

Oral Histone Deacetylase Inhibitor 4SC-202 in Patients With Advanced Hematologic Malignancies (TOPAS)

NCT01344707 ↗

Phase 1 Completed 36 enrolled 4SC AG
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine the Maximum Tolerated Dose, Dose Limiting Toxicities and optimal dosing schedule of 4SC-202 investigating its safety, tolerability and pharmacokinetics.

Timeline

Start
2011-03
Primary completion
2015-03
Completion
2015-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Domatinostat Small molecule — Oral