Dose Exploring and Setting Study for Tolvaptan to Treat Hepatic Cirrhosis With Ascites

Summary

To observe the safety/efficacy of tolvaptan for treatment of patients with hepatic cirrhosis with ascites and exploring the dosage-effect relations of the drug.

Timeline

Start

2009-04

Primary completion

2010-01

Completion

2010-04

Publications

• Wang S, Zhang X, Han T, Xie W, Li Y, Ma H, Liebe R, Weng H, Ding HG. Tolvaptan treatment improves survival of cirrhotic patients with ascites and hyponatremia. BMC Gastroenterol. 2018 Sep 4;18(1):137. doi: 10.1186/s12876-018-0857-0.

Drugs

Indications