Impact of Proteasome Inhibition on Anti-Donor HLA Antibody Production After Kidney Transplantation

Summary

The purpose of this study is to see if treating patients who have high levels of donor specific alloantibodies post-transplant with bortezomib might prevent the development of transplant glomerulopathy and preserve allograft function.

Timeline

Start

2011-12

Primary completion

2015-03

Completion

2015-03

Outcome

Outcome not reported

Stopped (Business): “Study halted due to lack of funding”

Drugs

Indications