drugset / Trial / NCT01351896

Lenalidomide and Vaccine Therapy in Treating Patients With Early-Stage Asymptomatic Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

NCT01351896

Phase 2 Active not recruiting 49 enrolled National Cancer Institute (NCI)
RandomizedParallel-groupOpen-labelTreatment

Summary

This phase II trial studies the effect of lenalidomide and vaccine in treating patients with early-stage asymptomatic chronic lymphocytic leukemia or small lymphocytic lymphoma. Lenalidomide may stop the growth of cancer cells by blocking blood flow to the cancer. It may also stimulate the immune system in different ways and stop cancer cells from growing. Vaccines may help the body build an effective immune response to kill cancer cells. Giving lenalidomide together with vaccine therapy may make a stronger immune response and kill more cancer cells.

Timeline

Start
2011-11-02
Primary completion
2024-07-08
Completion
2027-05-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenalidomide Other / unclassified Oral
Subject Pneumovax 23 Vaccine Intramuscular