drugset / Trial / NCT01352572

Effects of Antidepressant on Postsynaptic Signal Transduction in Serotonergic System of Depressed Patients

NCT01352572

Unknown 300 enrolled Samsung Medical Center
Non-randomizedParallel-groupDouble-blindTreatment

Summary

The purpose of this study is to determine whether alteration of signal transduction components after antidepressant targeting, predict antidepressant responsiveness in advance before the appearance of the drug effects until 4\~6 weeks after drug administration, or represent the clinical status of depressed patients.

Timeline

Start
2002-01
Primary completion
2018-12
Completion
2018-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Fluoxetine Small molecule
Subject Milnacipran Other / unclassified
Subject Mirtazapine Other / unclassified
Subject Nortriptyline Small molecule
Subject Paroxetine Small molecule
Subject Sertraline Small molecule
Subject Venlafaxine Small molecule

Indications