CRD007 for the Treatment of Abdominal Aorta Aneurysm (The AORTA Trial)

Summary

This is an investigation of the efficacy and safety of CRD007 compared to placebo in the treatment of patients with abdominal aortic aneurysm.

Timeline

Start

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Primary completion

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Completion

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Outcome

Missed primary endpoint

paper There was no statistically significant difference in growth between patients receiving placebo and those in the three dose groups of pemirolast. PMID 25963302 ↗

Publications

• Sillesen H, Eldrup N, Hultgren R, Lindeman J, Bredahl K, Thompson M, Wanhainen A, Wingren U, Swedenborg J; AORTA Trial Investigators. Randomized clinical trial of mast cell inhibition in patients with a medium-sized abdominal aortic aneurysm. Br J Surg. 2015 Jul;102(8):894-901. doi: 10.1002/bjs.9824. Epub 2015 May 12.

Drugs

Indications