drugset / Trial / NCT01354314
Study of Paroxetine and Fluconazole for the Treatment of HIV Associated Neurocognitive Disorder
Phase 1/2
Completed
45 enrolled
Johns Hopkins University
National Institute of Mental Health (NIMH) · collab
RandomizedFactorialTriple-blindTreatment
Summary
The purpose of this study is to see if paroxetine and fluconazole are safe and effective as a treatment for problems with memory, concentration, thinking, and judgment in people who are infected with HIV. Paroxetine is an antidepressant approved by the FDA to treat major depression. Fluconazole is an antifungal medication approved by the FDA to treat fungal infections.
Timeline
- Start
- 2010-11
- Primary completion
- 2016-03
- Completion
- 2016-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluconazole | Small molecule | 100 mg | Oral |
| Subject | Paroxetine | Small molecule | 20 mg | Oral |