CKD-828 Drug Interaction Study (S-amlodipine)

Phase 1 Completed 24 enrolled Chong Kun Dang Pharmaceutical Asan Medical Center · collab

RandomizedCrossoverOpen-labelTreatment

Summary

The purpose of this study is to evaluate the Pharmacokinetic drug interaction and safety of S-amlodipine between free combination of S-amlodipine and Telmisartan and S-amlodipine monotherapy.

Timeline

Start: 2011-05
Primary completion: 2011-08
Completion: 2011-08

Publications

Noh YH, Lim HS, Kim MJ, Kim YH, Choi HY, Sung HR, Jin SJ, Lim J, Bae KS. Pharmacokinetic interaction of telmisartan with s-amlodipine: an open-label, two-period crossover study in healthy Korean male volunteers. Clin Ther. 2012 Jul;34(7):1625-35. doi: 10.1016/j.clinthera.2012.05.010. Epub 2012 Jun 19.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	S-amlodipine	Unknown	5 mg	Oral
Subject	Telmisartan	Other / unclassified	80 mg	Oral

Indications

No indication recorded.