drugset / Trial / NCT01362231

A Study to Evaluate the Safety and Efficacy of GS-6624 (Formerly AB0024) in Patients With Idiopathic Pulmonary Fibrosis

NCT01362231

Phase 1 Completed 48 enrolled Gilead Sciences
RandomizedParallel-groupOpen-labelBasic science

Summary

The study consists of 2 parts: Part A is a randomized, multiple-dose, double-blind, placebo-controlled sequential dose escalation study to evaluate GS-6624 in subjects with Idiopathic Pulmonary Fibrosis (IPF) and was completed in October 2011. Part B is a randomized, two-dose, open-label dose expansion study to evaluate GS-6624 in subjects with IPF and is currently enrolling.

Timeline

Start
2010-12
Primary completion
2012-12
Completion
2012-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Simtuzumab Monoclonal antibody 125 mg Intravenous
Subject Simtuzumab Monoclonal antibody 200 mg Intravenous