drugset / Trial / NCT01367483

Study of the Pharmacokinetics of Intravenous Administered 14C-MNTX

NCT01367483

Phase 1 Completed 6 enrolled Bausch Health Americas, Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is an open-label, radiotracer study, to be conducted in healthy, normal, male volunteers. It will entail intravenous administration of a single dose of 14C-MNTX, collection of excretions, and periodic drawing of blood samples. Exhaled 14CO2 will also be sampled as a measure of the extent of possible metabolic MNTX demethylation.

Timeline

Start
2005-06
Primary completion
2005-06
Completion
2005-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylnaltrexone Other / unclassified Intravenous

Indications

No indication recorded.