drugset / Trial / NCT01367535
Effects of MNTX on CYP450 2D6 in Metabolizers of Dextromethorphan
RandomizedParallel-groupOpen-labelTreatment
Summary
This study is a single-center, randomized, open-label, active and placebo-controlled, parallel-group, conducted in healthy male volunteers who have been shown to be extensive metabolizers of dextromethorphan.
Timeline
- Start
- 2006-03
- Primary completion
- 2006-08
- Completion
- 2006-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Methylnaltrexone | Other / unclassified | — | Subcutaneous |
| Comparator | Paroxetine | Small molecule | — | Oral |
Indications
No indication recorded.