Mirasol-Treated Platelets - (Pathogen Reduction Extended Storage Study)

Summary

The PRESS trial is a single-center, two-part, randomized cross-over pilot study in Copenhagen that will evaluate 1) the safety and performance of Mirasol-treated and untreated platelet products stored for 2-4 days and for 7-days in Platelet Additive Solution (PAS) and 2) the correlation between the TEG® parameters and platelet count increments after platelet transfusions in thrombocytopenic subjects.

Timeline

Start

2010-09

Primary completion

2011-04

Completion

2011-05

Outcome

Outcome not reported

Stopped (Enrollment): “Part 1 completed, part 2 not done due to slow enrollment”

Publications

• Results Johansson PI, Simonsen AC, Brown PN, Ostrowski SR, Deberdt L, Van Hoydonck P, Yonemura SS, Goodrich RP. A pilot study to assess the hemostatic function of pathogen-reduced platelets in patients with thrombocytopenia. Transfusion. 2013 Sep;53(9):2043-52. doi: 10.1111/trf.12055. Epub 2012 Dec 24.

Drugs

Indications