drugset / Trial / NCT01369836
Study Of Single Doses Of PF-06291826 (Tafamidis) In Japanese And Western Subjects
RandomizedParallel-groupDouble-blindBasic science
Summary
The purpose of this study is the following: * To evaluate the safety, tolerability, and pharmacokinetics (PK) of orally administered tafamidis in Japanese and Western healthy volunteers at single dose. * To compare Japanese and Western PK profiles. * Determine the PD stabilization effect of tafamidis on human transthyretin (TTR) in a validated ex vivo assay.
Timeline
- Start
- 2011-07
- Primary completion
- 2011-08
- Completion
- 2011-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tafamidis | Unknown | 20 mg | Oral |
| Subject | Tafamidis | Unknown | 40 mg | Oral |
Indications
No indication recorded.