Step Up Versus Step Down in Controlled Ovarian Stimulation

Phase 4 Completed 158 enrolled Parc de Salut Mar

RandomizedParallel-groupOpen-labelTreatment

Summary

The aim of the study is to evaluate if the Step up protocol is equal or superior regarding efficacy and security than the step down protocol. In couple submitted two intrauterine insemination.

Timeline

Start: 2010-04
Primary completion: 2014-02
Completion: 2014-02

Publications

Robles A, Gayete-Lafuente S, Prat M, Gonzalez-Comadran M, Checa MA. The step-up protocol increases clinical pregnancy rates compared with the step-down in patients with unexplained infertility. A randomized controlled trial. JBRA Assist Reprod. 2022 Nov 9;26(4):599-605. doi: 10.5935/1518-0557.20210112.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	recombinant FSH	Protein / enzyme biologic	75 iu	Subcutaneous
Subject	recombinant FSH	Protein / enzyme biologic	150 iu	Subcutaneous

Step Up Versus Step Down in Controlled Ovarian Stimulation

Summary

Timeline

Publications

Drugs

Indications