Use of Azithromycin as Immunomodulatory Therapy in Grave&Apos;s Orbitopathy

Summary

The purpose of this study is to examine the effects of Azithromycin (a macrolide class antibiotic), given three times weekly, for patients with active moderate-severe, non sight-threatening, Graves Orbitopathy. Indices for follow-up will include: * Clinical activity score * Anti-TSH receptor antibody levels * Thickening of extraocular muscles per ultrasound * Quality of life score for Graves Orbitopathy patients

Timeline

Start

2011-05

Primary completion

2014-11

Completion

2014-12

Drugs

Indications