drugset / Trial / NCT01381562
GSK2251052 in the Treatment of Complicated Intra-abdominal Infections
RandomizedParallel-groupTriple-blindTreatment
Summary
This study is being conducted to evaluate the safety, efficacy and pharmacokinetics/pharmacodynamics of GSK2251052 in subjects with complicated intra abdominal infections. GSK2251052 will be compared to meropenem, an IV therapy that is approved for use in the treatment of subjects with cIAI. GSK2251052 has a spectrum of microbiological activity that includes pathogens responsible for cIAI.
Timeline
- Start
- 2011-10-03
- Primary completion
- 2012-03-05
- Completion
- 2012-03-05
Outcome
Outcome not reported
Stopped: “Microbiological findings of resistance on therapy in patients with complicated urinary tract infection”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Epetraborole | Small molecule | 750 mg | Intravenous |
| Subject | Epetraborole | Small molecule | 1500 mg | Intravenous |
| Comparator | Meropenem | Small molecule | 1 g | Intravenous |