drugset / Trial / NCT01381562

GSK2251052 in the Treatment of Complicated Intra-abdominal Infections

NCT01381562 ↗

Phase 2 Terminated 15 enrolled GlaxoSmithKline
RandomizedParallel-groupTriple-blindTreatment

Summary

This study is being conducted to evaluate the safety, efficacy and pharmacokinetics/pharmacodynamics of GSK2251052 in subjects with complicated intra abdominal infections. GSK2251052 will be compared to meropenem, an IV therapy that is approved for use in the treatment of subjects with cIAI. GSK2251052 has a spectrum of microbiological activity that includes pathogens responsible for cIAI.

Timeline

Start
2011-10-03
Primary completion
2012-03-05
Completion
2012-03-05

Outcome

Outcome not reported

Stopped: “Microbiological findings of resistance on therapy in patients with complicated urinary tract infection”

Drugs

EvaluationDrugModalityDoseRoute
Subject Epetraborole Small molecule 750 mg Intravenous
Subject Epetraborole Small molecule 1500 mg Intravenous
Comparator Meropenem Small molecule 1 g Intravenous