A Study of LY2979165 in Healthy Subjects
Summary
This is a two part study. Part A is a multiple-ascending dose study in up to 6 different groups of healthy subjects, with approximately 12 subjects in each of the groups. Part A will allow investigation of up to 6 different doses of LY2979165. The drug will be administered for a total of 14 days. Subjects will be resident in the clinical research unit (CRU) from Day -1 (the day before dosing) until Day 15. Part B will investigate a dose of LY2979165 previously administered in Part A in up to 12 subjects. The drug will be administered for a total of 14 days. In addition to the same assessments as would have been completed in Part A, subjects in Part B will also have cerebrospinal fluid samples taken from the lower lumbar region of their spine.
Timeline
- Start
- 2011-07
- Primary completion
- 2012-06
- Completion
- 2012-06
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | LY2979165 | Unknown | 20 mg | Oral |
| Subject | LY2979165 | Unknown | 60 mg | Oral |
| Subject | LY2979165 | Unknown | 100 mg | Oral |
| Subject | LY2979165 | Unknown | 150 mg | Oral |
| Subject | LY2979165 | Unknown | 250 mg | Oral |
| Subject | LY2979165 | Unknown | 400 mg | Oral |