drugset / Trial / NCT01383967

A Study of LY2979165 in Healthy Subjects

NCT01383967

Phase 1 Completed 102 enrolled Eli Lilly and Company
RandomizedParallel-groupDouble-blindTreatment

Summary

This is a two part study. Part A is a multiple-ascending dose study in up to 6 different groups of healthy subjects, with approximately 12 subjects in each of the groups. Part A will allow investigation of up to 6 different doses of LY2979165. The drug will be administered for a total of 14 days. Subjects will be resident in the clinical research unit (CRU) from Day -1 (the day before dosing) until Day 15. Part B will investigate a dose of LY2979165 previously administered in Part A in up to 12 subjects. The drug will be administered for a total of 14 days. In addition to the same assessments as would have been completed in Part A, subjects in Part B will also have cerebrospinal fluid samples taken from the lower lumbar region of their spine.

Timeline

Start
2011-07
Primary completion
2012-06
Completion
2012-06

Drugs

EvaluationDrugModalityDoseRoute
Subject LY2979165 Unknown 20 mg Oral
Subject LY2979165 Unknown 60 mg Oral
Subject LY2979165 Unknown 100 mg Oral
Subject LY2979165 Unknown 150 mg Oral
Subject LY2979165 Unknown 250 mg Oral
Subject LY2979165 Unknown 400 mg Oral

Indications