Effect of Propofol on Renal Injury in Patients Undergoing Valvular Heart Surgery

Summary

Ischemia/reperfusion (I/R)-induced acute kidney injury is a serious complication affecting patient outcome following cardiovascular surgeries. Propofol, an intravenously administered anesthetic with antioxidant properties, protects organs from I/R injury. This study aimed to investigate the ability of propofol to protect kidneys against I/R injury in the patients undergoing valvular heart surgery.

Timeline

Start

2011-05

Primary completion

2012-05

Completion

2012-05

Drugs

Indications