BKM120 in Metastatic Castration-resistant Prostate Cancer

Summary

The purpose of this study is to evaluate the effects of the study drug, BKM120. The study drug, BKM120, is an inhibitor of a protein called phosphatidyl inositol-3-kinase (PI3K). This protein is found in normal cells and in cancer cells, but often in many cancer cells this protein is overactive. Inhibiting the protein may slow the growth of prostate cancer but this has not been tested yet in men with prostate cancer.

Timeline

Start

2011-08

Primary completion

2016-02

Completion

2016-02

Outcome

Outcome not reported

Stopped: “The trial was stopped at the first stage due to futility”

Drugs

Indications