Menadione Topical Lotion in Treating Skin Discomfort and Psychological Distress in Patients With Cancer Receiving Panitumumab, Erlotinib Hydrochloride, or Cetuximab

Summary

This clinical trial studies menadione topical lotion in treating skin discomfort and psychological distress in patients with cancer receiving panitumumab, erlotinib hydrochloride, or cetuximab. Menadione topical lotion may prevent rash or other skin discomfort and help alleviate psychological distress and pain in patients receiving treatment with panitumumab, erlotinib hydrochloride, or cetuximab

Timeline

Start

2012-01-23

Primary completion

2013-05-11

Completion

2018-07-14

Outcome

Missed primary endpoint

registry analysis (superiority test); Arm A (Menadione) vs Arm B (Placebo); p = 0.6311; Kruskal-Wallis NCT01393821 ↗

Drugs

Indications