Effects of Dronabinol (Oral THC) on Cannabis Use

Phase 1/2 Completed 25 enrolled Johns Hopkins University National Institute on Drug Abuse (NIDA) · collab

RandomizedSingle-groupDouble-blindBasic science

Summary

Study participants received dronabinol (0, 120mg/day and 240mg/day) for 12 consecutive days in a randomized order. During each dronabinol maintenance period they were able to self-administer active or placebo cannabis using either a progressive ratio schedule or choice between cannabis and monetary alternative.

Timeline

Start: 2011-02
Primary completion: 2012-09
Completion: 2012-09

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Dronabinol	Other / unclassified	40 mg	Oral
Comparator	Dronabinol	Other / unclassified	80 mg	Oral

Indications

No indication recorded.