Treating Acutely Agitated Patients With Asenapine Sublingual Tablets

Phase 4 Completed 120 enrolled Unity Health Toronto Schering-Plough · collab

RandomizedParallel-groupQuadruple-blindTreatment

Summary

Our proposal is to administer asenapine to patients who are clinically agitated and in need of immediate intervention. At present there are no controlled studies that we know of that explores the use of asenapine for this purpose. Establishing the utility of asenapine for this common clinical problem will support its use as an additional treatment option in acutely agitated patients.

Timeline

Start: 2012-04
Primary completion: 2012-12
Completion: 2012-12

Publications

Pratts M, Citrome L, Grant W, Leso L, Opler LA. A single-dose, randomized, double-blind, placebo-controlled trial of sublingual asenapine for acute agitation. Acta Psychiatr Scand. 2014 Jul;130(1):61-8. doi: 10.1111/acps.12262. Epub 2014 Mar 10.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Asenapine	Other / unclassified	10 mg	Other

Indications

No indication recorded.