drugset / Trial / NCT01405677

Safety and Immunogenicity of a Paediatric Dose of Virosomal Hepatitis A Vaccine

NCT01405677

Phase 2 Completed 308 enrolled Crucell Holland BV
RandomizedParallel-groupOpen-labelPrevention

Summary

The primary purpose of the original study was to assess whether the protection afforded by the paediatric dose of Epaxal vaccine against hepatitis A was not inferior to the protection afforded by the standard dose of Epaxal. The aim of the follow-up phase was to perform a computer based modelling analysis of the long term protection afforded by the paediatric dose, and to compare this with the standard dose and also with an alternative hepatitis A vaccine (Havrix Junior).

Timeline

Start
2004-06
Primary completion
2012-04
Completion
2012-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Epaxal Vaccine 0.25 ml Intramuscular
Subject Epaxal Vaccine 0.5 ml Intramuscular
Comparator Havrix Junior Vaccine 0.5 ml Intramuscular