drugset / Trial / NCT01407107
Dose Escalation Trial of Nitroglycerin, 5-flourouracil and Rad Therapy for Rectal Cancer
Phase 1
Completed
13 enrolled
University of Texas Southwestern Medical Center
US Department of Veterans Affairs · collab
NaSingle-groupOpen-labelTreatment
Summary
The purpose of this study is to determine whether topical nitroglycerin in addition to 5-flourouracil and radiation therapy are effective in the treatment of operable rectal cancer.
Timeline
- Start
- 2011-01
- Primary completion
- 2015-10
- Completion
- 2016-10
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Nitroglycerin | Unknown | 0.2 mg | Other |
| Subject | Nitroglycerin | Unknown | 0.4 mg | Other |
| Subject | Nitroglycerin | Unknown | 0.6 mg | Other |