drugset / Trial / NCT01408524

Control of Emergence Blood Pressure During Craniotomy for Tumor Surgery Between Labetolol and Diltiazem

NCT01408524

Phase 1/2 Completed 184 enrolled Mahidol University
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to determine the effectiveness of the antihypertensive drugs in the control of emergence blood pressure after tumor resection craniotomy; compared between labetalol (Avexa) and diltiazem (Herbessor). Also the investigators seek to determine the effective dose of the antihypertensive drugs and their side effects in Thai population.

Timeline

Start
2010-02
Primary completion
2012-11
Completion
2013-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Diltiazem Small molecule 2.5 mg Intravenous
Comparator Labetalol Small molecule 2.5 mg Intravenous

Indications