drugset / Trial / NCT01408797

Clonal Deletion on Living-Relative Donor Kidney Transplantation

NCT01408797

Non-randomizedSingle-groupOpen-labelTreatment

Summary

The objective of this trial is to determine if clonal deletion before kidney transplantation can effectively reduce the need for post transplant immunosuppression. The investigators will adapt a DAWN (Drugs (immunosuppressants) Added When Needed) treatment protocol to assess the effect of clonal deletion and closely monitor acute rejection, renal function, and graft survival. 15 patients eligible for the study as described below will be enrolled.

Timeline

Start
2011-03
Primary completion
2013-03
Completion
2013-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Bortezomib Small molecule
Subject MMF Unknown

Indications