drugset

drugset / Trial / NCT01408836

Plasma Exchange for Renal Vasculitis

NCT01408836 ↗

Phase 2/3 Terminated 150 enrolled Cambridge University Hospitals NHS Foundation Trust Fundacio Clinic Barcelona · collab Imperial College London · collab London North West Healthcare NHS Trust · collab Lund University Hospital · collab University Hospital Birmingham · collab University Hospitals, Leicester · collab University Medical Center Groningen · collab University of Helsinki · collab

RandomizedParallel-groupOpen-labelTreatment

Summary

The purpose of this study is to test whether additional therapy with plasma exchange improves the chances of kidney recovery in severe kidney vasculitis.

Timeline

Start: 1995-03
Primary completion: 2003-06
Completion: 2003-12

Publications

Walsh M, Casian A, Flossmann O, Westman K, Hoglund P, Pusey C, Jayne DR; European Vasculitis Study Group (EUVAS). Long-term follow-up of patients with severe ANCA-associated vasculitis comparing plasma exchange to intravenous methylprednisolone treatment is unclear. Kidney Int. 2013 Aug;84(2):397-402. doi: 10.1038/ki.2013.131. Epub 2013 Apr 24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Methylprednisolone	Other / unclassified	1000 mg	Intravenous

Indications