drugset / Trial / NCT01411670

Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock.

NCT01411670

Phase 2 Completed 60 enrolled University of Roma La Sapienza
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The purpose of this study is to investigate the effects on systemic hemodynamics, microcirculation and organ function of human Protein C concentrate in patients with sepsis and septic shock.

Timeline

Start
2011-01
Primary completion
2015-02
Completion
2015-04

Drugs

EvaluationDrugModalityDoseRoute
Comparator Drotrecogin alfa (activated) Protein / enzyme biologic 24 ug/kg
Subject Human protein C concentrate Protein / enzyme biologic 3 iu/kg