drugset
drugset / Trial / NCT01413620

Vitamin E Supplementation in Burn Patients

NCT01413620 ↗

Phase 1 Withdrawn Shriners Hospitals for Children Oregon State University · collabUniversity of Texas · collab
RandomizedParallel-groupSingle-blindTreatment

Summary

Burned patients because of their increased oxidative stress have severely depleted vitamin E, which is a dietary antioxidant. Oxidative stress is responsible for much of the pathophysiology seen in burned patients, which leads to acute and chronic morbidity and mortality, in addition to a decrease in their quality of life. Oral vitamin E will be used to reverse the oxidative stress of burn injury and, in the process, decrease the secondary consequences of thermal trauma. This proposal will demonstrate the benefit of maintaining adequate vitamin E status.

Timeline

Start
2011-08
Primary completion
2017-08
Completion
2021-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Dl-Alpha Tocopheryl Acetate Unknown 75 iu Oral
Subject Dl-Alpha Tocopheryl Acetate Unknown 150 iu Oral
Subject Dl-Alpha Tocopheryl Acetate Unknown 300 iu Oral
Subject Dl-Alpha Tocopheryl Acetate Unknown 600 iu Oral
Subject Dl-Alpha Tocopheryl Acetate Unknown 800 iu Oral
Subject Dl-Alpha Tocopheryl Acetate Unknown 1200 iu Oral

Indications

No indication recorded.