drugset / Trial / NCT01420211
Influence of the OATP1B1 and OATP1B3 Genotype on the Hepatic Uptake of Primovist®
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The objective of the study is to assess the hepatic uptake of Primovist® after intravenous administration of 25 µmol/kg body weight in 56 healthy volunteers and in 60 patients with a liver disease in dependence on the OATP1B1- and OATP1B3-genotype.
Timeline
- Start
- 2006-10
- Primary completion
- 2010-07
- Completion
- 2010-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Gadoxetate Disodium | Diagnostic / imaging agent | 25 unknown | Intravenous |