drugset / Trial / NCT01425216

Sorafenib for Patients With Extensive Keloids

NCT01425216 ↗

Phase 2 Terminated 60 enrolled Tirgan, Michael H., M.D.
NaSingle-groupOpen-labelTreatment

Summary

Treatment of keloid disorder is an area of unmet medical need. Current treatments for keloid partially address small and localized keloids, yet there are no wholly satisfactory or effective treatments for patients with extensive keloids. Such patients may benefit from effective systemic treatments. Sorafenib has the potential to regulate the three known dysregulated biological pathways in keloid tissue.

Timeline

Start
2013-03
Primary completion
2013-03
Completion
2013-03

Outcome

Outcome not reported

Stopped: “IND application was not approved by the US FDA - Project was never started”

Drugs

EvaluationDrugModalityDoseRoute
Subject Sorafenib Small molecule 400 mg Oral

Indications