Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy

Phase 4 Completed 38 enrolled Mustafa Kemal University Novartis Pharmaceuticals · collab

RandomizedSingle-groupOpen-labelTreatment

Summary

The study hypothesis: Valsartan as an angiotensin II receptor blocker treatment has beneficial effects on both midwall mechanics and myocardial functions in hypertensive patients with Left ventricular hypertrophy.

Timeline

Start: 2006-11
Primary completion: 2008-11
Completion: 2008-11

Publications

Kucukler N, Kurt IH, Topaloglu C, Gurbuz S, Yalcin F. The effect of valsartan on left ventricular myocardial functions in hypertensive patients with left ventricular hypertrophy. J Cardiovasc Med (Hagerstown). 2012 Mar;13(3):181-6. doi: 10.2459/JCM.0b013e3283511f00.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Hydrochlorothiazide	Unknown	12.5 mg	—
Subject	Valsartan	Small molecule	80 mg	—
Subject	Valsartan	Small molecule	160 mg	—

Effect of Valsartan on Left Ventricular Myocardial Functions in Hypertensive Patients With Left Ventricular Hypertrophy

Summary

Timeline

Publications

Drugs

Indications