Dopamine Versus Dobutamine for Treatment of Arterial Hypotension in Term and Preterm Neonates

Summary

The purpose of this study is to examine the effects of Dobutamine as compared to Dopamine in term and preterm neonates with arterial hypotension on cerebral and renal oxygenation, fractional tissue oxygen extraction, mean arterial blood pressure and cardiac output. The investigators hypothesize that Dopamine has a stronger effect on blood pressure than Dobutamine but Dobutamine has a stronger effect on cerebral oxygenation and cardiac output than Dopamine.

Timeline

Start

2011-06

Primary completion

2015-02

Completion

2016-12

Drugs

Indications