drugset / Trial / NCT01429337

PK and Safety of Midostaurin in Subjects With Impaired Hepatic Function and Subjects With Normal Hepatic Function

NCT01429337

Phase 1 Completed 43 enrolled Novartis Pharmaceuticals
Non-randomizedParallel-groupOpen-labelBasic science

Summary

The purpose of this international study was to assess the effect of varying degrees of impaired hepatic function compared to a normal hepatic function (Child-Pugh classification) on the pharmacokinetics and safety of midostaurin.

Timeline

Start
2011-03-07
Primary completion
2020-04-13
Completion
2020-05-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Midostaurin Small molecule 50 mg Oral

Indications

No indication recorded.