drugset / Trial / NCT01432496
Peritoneal Nebulization of Ropivacaine for Pain Control After Laparoscopic Colectomy
Phase 3
Terminated
130 enrolled
San Gerardo Hospital
Azienda Ospedaliera di Lecco · collabFondazione IRCCS Policlinico San Matteo di Pavia · collabUniversity of Milano Bicocca · collabUniversity of Pavia · collab
RandomizedParallel-groupQuadruple-blindTreatment
Summary
The purpose of this study is to assess if intraperitoneal nebulization of Ropivacaine 150 mg produces better postoperative pain control than Saline nebulization after laparoscopic colectomy.
Timeline
- Start
- 2011-09
- Primary completion
- 2012-12
- Completion
- 2012-12
Outcome
Outcome not reported
Stopped (Enrollment): “There was insuficient recruitment in two centers”
Publications
- Background Alkhamesi NA, Peck DH, Lomax D, Darzi AW. Intraperitoneal aerosolization of bupivacaine reduces postoperative pain in laparoscopic surgery: a randomized prospective controlled double-blinded clinical trial. Surg Endosc. 2007 Apr;21(4):602-6. doi: 10.1007/s00464-006-9087-6. Epub 2006 Dec 16.
- Background Greib N, Schlotterbeck H, Dow WA, Joshi GP, Geny B, Diemunsch PA. An evaluation of gas humidifying devices as a means of intraperitoneal local anesthetic administration for laparoscopic surgery. Anesth Analg. 2008 Aug;107(2):549-51. doi: 10.1213/ane.0b013e318176fa1c.
- Background Schlotterbeck H, Schaeffer R, Dow WA, Diemunsch P. Cold nebulization used to prevent heat loss during laparoscopic surgery: an experimental study in pigs. Surg Endosc. 2008 Dec;22(12):2616-20. doi: 10.1007/s00464-008-9841-z. Epub 2008 Mar 18.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ropivacaine | Other / unclassified | 150 mg | Other |
Indications
No indication recorded.