drugset / Trial / NCT01434069
Phase I Trial of Combination of FOLFIRI and SOM 230
NaSingle-groupOpen-labelTreatment
Summary
This is a single-arm, open-label, phase I study of combination therapy with SOM 230 and FOLFIRI. We will utilize a sequential dose-escalation design to define the maximum tolerated dose (MTD) of SOM 230 when combined with standard doses of FOLFIRI.
Timeline
- Start
- 2011-09
- Primary completion
- 2015-12
- Completion
- 2015-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Pasireotide | Other / unclassified | — | Intramuscular |
| Background | Leucovorin | Small molecule | — | Intravenous |
| Background | fluorouracil | Small molecule | — | Intravenous |
| Background | irrinotecan | Unknown | — | Intravenous |