Continuous Intraventricular Methotrexate in Treating Patients With Leptomeningeal Disease

Summary

This pilot clinical trial studies continuous intraventricular methotrexate in treating patients with leptomeningeal disease. Drugs used in chemotherapy, such as methotrexate, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving drugs directly into the ventricles may be an effective treatment for patients with leptomeningeal disease

Timeline

Start

2012-09

Primary completion

2013-11

Completion

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Drugs

Indications