drugset / Trial / NCT01439152

Phase I Study to Determine the Maximum Tolerable Dose of BAY94-9343 in Patients With Advanced Solid Tumors.

NCT01439152

Phase 1 Completed 148 enrolled Bayer
Non-randomizedParallel-groupOpen-labelTreatment

Summary

BAY94-9343 was an antibody-drug conjugate (ADC) directed against the cancer antigen mesothelin on tumor cells.

Timeline

Start
2011-09-07
Primary completion
2016-12-31
Completion
2019-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Anetumab Ravtansine Monoclonal antibody 0.15 mg/kg Intravenous
Subject Anetumab Ravtansine Monoclonal antibody 1.8 mg/kg Intravenous
Subject Anetumab Ravtansine Monoclonal antibody 2.2 mg/kg Intravenous
Subject Anetumab Ravtansine Monoclonal antibody 5.5 mg/kg Intravenous

Indications

No indication recorded.