drugset / Trial / NCT01443702

Use of Lapis Judaicus to Dissolve Kidney Stones

NCT01443702 ↗

Phase 1/2 Completed 60 enrolled Shiraz University of Medical Sciences
RandomizedParallel-groupQuadruple-blindTreatment

Summary

The investigators will investigate the safety and effectiveness of an Iranian traditional medicine regarding its ability to dissolve existing kidney stones. Calcium stone formers will be recruited for a 12 week trial. Each subject will receive Lapis judaicus or placebo in random order. End points are changes in urinary chemistries and stone burden by Ultra sonography / CT scan. It will be used in proven calcium stone forming adults who are not pregnant. This phase is a double blind, randomized, placebo controlled Entry, first and 12 week 24 hour urine supersaturations, pH and sodium determinations will be collected. Entry and final stone quantification Ultra sonography / CT scan will be performed. End points will be changes in urine chemistry/supersaturation and stone quantitative stone volume.

Timeline

Start
2011-01
Primary completion
2011-12
Completion
—

Drugs

EvaluationDrugModalityDoseRoute
Comparator Lapis Judaicus Traditional medicine (herbal / TCM) 2 g —

Indications