Study of an Investigational Pneumococcal Vaccine at Three Dose Levels in Healthy Adults

Summary

This study is designed to evaluate the safety, tolerability, and immunogenicity of an investigational pneumococcal vaccine in healthy adult volunteers. Primary Objective: * To evaluate the safety and tolerability of an investigational pneumococcal vaccine. Observational Objective: * To evaluate the immunogenicity of an investigational Pneumococcal vaccine.

Timeline

Start

2010-06

Primary completion

2011-01

Completion

2011-01

Publications

• Kamtchoua T, Bologa M, Hopfer R, Neveu D, Hu B, Sheng X, Corde N, Pouzet C, Zimmermann G, Gurunathan S. Safety and immunogenicity of the pneumococcal pneumolysin derivative PlyD1 in a single-antigen protein vaccine candidate in adults. Vaccine. 2013 Jan 2;31(2):327-33. doi: 10.1016/j.vaccine.2012.11.005. Epub 2012 Nov 12.

Drugs

Indications