Effect of Colloid Versus Crystalloid on Coagulation

Phase 4 Unknown 40 enrolled K. C. Rasmussen

RandomizedParallel-groupDouble-blindPrevention

Summary

In order to reduce bloodloss and need for transfusion to investigate the effect of colloid and crystalloid on coagulation assuming no difference between the groups.

Timeline

Start: 2011-09
Primary completion: 2013-04
Completion: 2013-12

Publications

Rasmussen KC, Johansson PI, Hojskov M, Kridina I, Kistorp T, Thind P, Nielsen HB, Ruhnau B, Pedersen T, Secher NH. Hydroxyethyl starch reduces coagulation competence and increases blood loss during major surgery: results from a randomized controlled trial. Ann Surg. 2014 Feb;259(2):249-54. doi: 10.1097/SLA.0000000000000267.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Ringer-lactate "SAD"	Unknown	35 unknown	Intravenous
Comparator	Volulyte	Other / unclassified	35 unknown	Intravenous

Indications

No indication recorded.