drugset / Trial / NCT01445028

Isotretinoin for Proliferative Vitreoretinopathy

NCT01445028

Phase 4 Completed 109 enrolled Wills Eye
Non-randomizedParallel-groupOpen-labelPrevention

Summary

Proliferative vitreoretinopathy (PVR), or secondary scarring on and around the retina, is an important cause of retinal re-detachment. The purpose of this study is to evaluate the effect of oral isotretinoin, which inhibits the growth of cells responsible for proliferative vitreoretinopathy (PVR), on recurrent retinal detachment.

Timeline

Start
2011-09
Primary completion
2013-08
Completion
2015-08

Drugs

EvaluationDrugModalityDoseRoute
Subject Isotretinoin Other / unclassified 20 mg Oral