drugset / Trial / NCT01446978
Three Doses of Hepatitis A Vaccine in Patients With Immunomodulating Drugs
RandomizedParallel-groupOpen-labelPrevention
Summary
Hepatitis A vaccine is the most frequently used traveler's vaccine, yet data on its ability to induce protective immunity in immunosuppressed travelers are scarce. The investigators assess the hepatitis A virus (HAV) antibody response in patients with rheumatoid arthritis (RA) treated with Tumor Necrosis Factor (TNF) - inhibitors and/or methotrexate (Mtx). In a previous study, 2 doses were not considered effective and there is therefore need for a study with an additional dose
Timeline
- Start
- 2011-09
- Primary completion
- 2016-08
- Completion
- 2016-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Havrix | Vaccine | — | — |
Indications
No indication recorded.