drugset / Trial / NCT01446978

Three Doses of Hepatitis A Vaccine in Patients With Immunomodulating Drugs

NCT01446978

Phase 2 Unknown 150 enrolled Sormland County Council, Sweden
RandomizedParallel-groupOpen-labelPrevention

Summary

Hepatitis A vaccine is the most frequently used traveler's vaccine, yet data on its ability to induce protective immunity in immunosuppressed travelers are scarce. The investigators assess the hepatitis A virus (HAV) antibody response in patients with rheumatoid arthritis (RA) treated with Tumor Necrosis Factor (TNF) - inhibitors and/or methotrexate (Mtx). In a previous study, 2 doses were not considered effective and there is therefore need for a study with an additional dose

Timeline

Start
2011-09
Primary completion
2016-08
Completion
2016-08

Drugs

EvaluationDrugModalityDoseRoute
Comparator Havrix Vaccine

Indications

No indication recorded.