Lubiprostone and Mucus Secretion in Patients With Chronic Constipation

Summary

The investigators hypothesize that the symptoms of chronic constipation in some patients are developed due to diminished production and secretion of the alimentary tract mucus resulting in poor lubrication. Therefore, the investigators assume that administration of lubiprostone may restore this lubrication impairment by stimulation of mucus production and secretion within the gastrointestinal tract.

Timeline

Start

2011-08

Primary completion

2012-11

Completion

2012-11

Drugs

Indications